Max Planck Institute for Metabolism Research

The overarching research goal of the MPI for Metabolism Research is thus to define the physiological regulatory principles in energy and glucose homeostasis as well as the genetic factors and environmental cues that alter energy and glucose homeostasis in disease. By achieving this goal, we aim to ultimately identify novel therapeutic targets as a first step to developing new treatments for obesity and obesity-associated diseases. To this end, researchers of the Institute employ state-of-the-art methodologies and technologies to pursue translational research approaches ranging from studies on unravelling the underlying molecular mechanisms in cultured cells to defining regulatory mechanisms in model organisms. Finally, hypotheses derived from these approaches are tested and validated through functional imaging in control human subjects as well as patients suffering from obesity and obesity-associated diseases.